Wisdom is personified in Proverb 8. As a literary device, its feminine aspect carries some story-lesson value.
The word "wisdom" (Chokmah, חכמה) being linguistically a feminine gender is a Hebrew grammatical issue that does not carry weight into theological significance. Interestingly, the Greek word for wisdom (sophia, σοφία) is also feminine and Paul had no problem talking about it as if it was a man in
1 Corinthians 1:24
but to those whom God has called, both Jews and Greeks, Christ the power of God and the wisdom of God. ...
30 It is because of him that you are in Christ Jesus, who has become for us wisdom from God--that is, our righteousness, holiness and redemption.
Theologically as far as creative construction is concerned, we see the role of the Son of God in
John 1:1 In the beginning was the Word, and the Word was with God, and the Word was God. 2He was with God in the beginning. 3Through Him all things were made, and without Him nothing was made that has been made.
In both Hebrew and Greek, it is a linguistic issue, not a sex or theological issue.