The "curse" is a reference to sin and sinners. Those who are sinners still when probation closes will be "cut off" and will no longer exist.
For such as be blessed of him shall inherit the earth; and they that
be cursed of him shall be cut off. (Psalm 37:22, KJV)
Then shall he say also unto them on the left hand, Depart from me, ye
cursed, into everlasting fire, prepared for the devil and his angels:
(Matthew 25:41, KJV)
That final pronouncement which ends this saga is found in the same chapter of Revelation.
He that is unjust, let him be unjust still: and he which is filthy,
let him be filthy still: and he that is righteous, let him be
righteous still: and he that is holy, let him be holy still.
(Revelation 22:11, KJV)
Those that are "unjust" or "filthy" at this point in time are forever cursed. They will not inherit eternal life.
But, even after the curse of sin is over, wounds from sin remain. Those wounds will take some time to heal. This is why we have the reference to the leaves of the Tree of Life being for the healing of the nations.
In the midst of the street of it, and on either side of the river, was
there the tree of life, which bare twelve manner of fruits, and
yielded her fruit every month: and the leaves of the tree were for the
healing of the nations. (Revelation 22:2, KJV)
During the first thousand years in heaven, before the saints return to Earth to take up residence in the earth made new, they will have opportunity to go over the books of record (see 1 Cor. 6:3) and to understand why some among their friends and loved ones are not there. I would submit that they may still shed some tears during this time, for it is at the close of the thousand years that the Bible says God will wipe away their tears.
And I saw a new heaven and a new earth: for the first heaven and the
first earth were passed away; and there was no more sea. (Revelation
And I John saw the holy city, new Jerusalem, coming down from God out
of heaven, prepared as a bride adorned for her husband. (Revelation
And I heard a great voice out of heaven saying, Behold, the tabernacle
of God is with men, and he will dwell with them, and they shall be his
people, and God himself shall be with them, and be their God.
(Revelation 21:3, KJV)
And God shall wipe away all tears from their eyes; and there shall be
no more death, neither sorrow, nor crying, neither shall there be any
more pain: for the former things are passed away. (Revelation 21:4,
In those verses we see that, first, there is a new earth, secondly, the New Jerusalem comes out of heaven and down to this new earth, and thirdly, the "no more tears" pronouncement comes with "no more death, neither sorrow, nor crying," clearly placing this after hell has cleaned up the mess of sin. Once hell is past, the saints will have had closure, and they will cry no more.
The thousand-year period in heaven (the millennium) will be a time for healing from sin, for though sin itself no longer troubles the saints, the wounds from sin and the memories of sin do still exist.