In John 5 Jesus had healed a man on the sabbath:
Jesus said to him, “Get up, take up your bed, and walk.” And at once the man was healed, and he took up his bed and walked. Now that day was the Sabbath. John 5:8-9 ESV
Afterwards the Jews started persecuting Jesus for this:
And this was why the Jews were persecuting Jesus, because he was doing these things on the Sabbath. But Jesus answered them, “My Father is working until now, and I am working.” This was why the Jews were seeking all the more to kill him, because not only was he breaking the Sabbath, but he was even calling God his own Father, making himself equal with God. - John 5:16-18
Then Jesus starts a long discourse to the Jews, beginning:
So Jesus said to them, (...) - John 5:19 - first 5 words - ESV
Later on Jesus proceeds to ask them how could they believe (in Him v.43):
I have come in my Father’s name, and you do not receive me. If another comes in his own name, you will receive him. John 5:43 - ESV
Because they were receiving glory from one another and not seeking the glory the comes from God:
How can you believe, when you receive glory from one another and do not seek the glory that comes from the only God? John 5:44 - ESV
What is the glory that comes from God?