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In Mark 1:24, a demon tells Jesus "I know who you are—the Holy One of God!" This title is surprising since the title "the Son of God" is used to introduce Jesus in 1:1. Obviously the title denotes Jesus' holiness here, but what connotations would it have had? Is it a kingly title? Priestly title? Divine title?

In the New Testament it's used in the parallel passage in Luke 4:34, but also in John 6:69 in a passage reminiscent of Peter's confession in Mark 8 of Jesus as the "Son of God." But I couldn't find other usages of the title in a wider search. Was this a known title at the time? If so, what are its roots?

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I found this very interesting. hebrew4christians.com/Names_of_G-d/Holy_One/holy_one.html –  John Martin May 19 at 0:51

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The Septuagint (LXX) mentions the "the Holy One of Israel" (τοῦ θεοῦ ... τοῦ ἁγίου Ισραηλ) in Isaiah 55:5, and the reference is to King David, who is the anointed one. (Ps 16:10 also mentions "your Holy One," but uses instead "οὐδὲ δώσεις τὸν ὅσιόν σου ἰδεῖν διαφθοράν" in reference to the anointed one, who appears to be King David in the immediate context.) The spirits addressing Jesus as the "Holy One" appear to be referring to him as the anointed, because he (Jesus) later admonishes them not to disclose that he is the Christ (Luke 4:41). For those demons who did not heed, their apparent fate included consignment to the torment of the abyss (Luke 8:28-31).

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David called the LORD "Holy One" in Psalm 16:10. "Holy One of Israel" appears numerous time in the O.T., mainly in Isaiah. The connotation of the Holy One of God would have to be Divine, and certainly the result for the action would be Powerful. Satin could not and can not resist the power of God. It couldn't be kingly since there was no kingdom at that time. It could have a priestly title since He was there to preach and teach. However I think the demon was attributing Jesus with having God's almighty power.

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